[1] The Dynamo missed the playoffs in 2020 for the 6th time in 7 years, finishing last in the Western Conference.

2020 was the Dynamo's first year with head coach Tab Ramos and the sixth season under General Manager Matt Jordan.

Per Major League Soccer and club policies terms of the deals do not get disclosed.

Games during the group stage counted as regular season matches.

[27] As an MLS club, the Dynamo was originally set to enter the competition in the Third or Fourth Round, tentatively scheduled for April 21–23 or May 19–20.