The Bears won their 10th conference championship (shared with South Dakota State) and returned the playoffs for the first time since 1990.

Junior wide receiver Damoriea Vick and Senior cornerback Zack Sanders were the players chosen, both as honorable mentions.

Director of football operations Lynn Mentzer was the only person retained from the Dave Steckel era.

Former Central Michigan special teams and safeties coach Ryan Beard, joined the Bears as the defensive coordinator.

Nick Petrino joined the Bears as the offensive coordinator/ quarterbacks coach after spending the previous season at UT Martin in the same capacity.

Quarterback Running back Wide receiver Tight end Punter Offensive lineman Defensive lineman Long snapper Linebacker Cornerback Defensive back Safety Placekicker Source:[4] Missouri State had a game scheduled against Tarleton State,[5] and Montana[6] which were later canceled due to the COVID-19 pandemic.

The opener against Illinois State was postponed to April 17 after winter storms made the playing surface unplayable after it was covered in snow and ice.

Both teams exchanged turnovers early in the first quarter and Hayden Ray missed a chip shot field goal.

Missouri State opened the second half scoring with a Jose Pizano 31 yard field goal to extend the lead to 20–7 with 8:47 left in the quarter.

UCA would strike on a Breylin Smith seven-yard pass to Tyler Hudson; the extra point was missed and MSU led by 7.

QB Jaden Johnson fumbled on the first play of the quarter which was returned by Dre Matthews for a touchdown.

Jose Pizano kicked a 30-yard field goal as time expired to put Missouri State up 24–17 at the half.

UCA scored 16 unanswered points in the third quarter on three field goals from Hayden Ray and Breylin Smith's second touchdown pass of the game.

[14] at Plaster Stadium • Springfield, MO The Bears traveled to Hanson Field in Macomb, Illinois for their first game of the Spring and first MVFC matchup.

Missouri State jumped out to a 14-point lead in the first quarter from a five-yard rushing touchdown from Celdon Manning and 11-yard run from Jeremiah Wilson.

Dennis Houston scored on six-yard pass from Connor Sampson after Jaden Johnson his first interception of the game.

Jaden Johnson threw his first touchdown pass as a Bear when he connected with Isaac Smith for a 22-yard score.

Jose Pizano kicked his third field goal of the game to put the Bears up 30–24 when he converted from 33 yards.

[15] at Hanson Field • Macomb, IL The Bears returned home following the win at Western Illinois for a matchup with the #6 North Dakota State Bison.

The Bears defense allowed two big plays to hand North Dakota State control.

Missouri State fought back in the second quarter with Jose Pizano kicking a 21-yard field goal.

It stayed tied through the half and most of the 3rd till South Dakota added seven more on a Carson Camp 36-yard touchdown pass to Carter Bell.

Eric Johnson blocked a 44-yard field goal attempt by Mason Lorber to preserve the tie.