[1] On September 10, 2020, it was reported that the 2020 NCAA Division I Men's Soccer Tournament would tentatively be rescheduled from April 30 to May 17, 2021.

[3] The College Cup was moved from Santa Barbara, California to Cary, North Carolina.

[5] Due to the ongoing COVID-19 pandemic, the 2020 edition of the NCAA Division I Men's Soccer Tournament featured only 36 teams.

This included the champions of the ACC and Sun Belt, which held their conference championships in fall 2020.

Omaha April 20, 2021 1 (2017) First round (2017) Rather than the higher seed hosting the early-round matches, the entire tournament was played in the state of North Carolina, similar to how the 2021 men's and women's basketball tournaments were held in a single state.