The 2020 Nashville SC season was the club's first season as an organization and its first season as a member of Major League Soccer, after two seasons in the Eastern Conference of the USL Championship by a club of the same name.

Despite a brief stint in the Western Conference, the club moved to the Eastern Conference after the MLS is Back Tournament.

[1] Additional source for roster transaction dates:[31] Win Draw Loss Postponed As a new MLS club, Nashville was scheduled to enter the competition in the Third Round, to be played April 21–23.

[38] The ongoing coronavirus pandemic, however, forced the U.S. Soccer Federation to cancel the tournament on August 17, 2020.

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