Strade Bianche (both the men's race and the women's race) was originally scheduled for 7 March 2020 but was postponed to 1 August 2020 due to the COVID-19 pandemic.

[1] Starting and finishing in Siena, Italy, Strade Bianche is the second event of the 2020 UCI Women's World Tour.

The route is identical to that of the previous years, containing 30 km (19 mi) of gravel roads spread over eight sectors, for a total distance of 136 km (85 mi).

[2] Eight UCI Women's WorldTeams and fourteen UCI Women's Continental Teams made up the twenty-two teams that competed in the race.

[3] The day before the race, Ashleigh Moolman of CCC Liv, Ella Harris of Canyon–SRAM, and Clara Koppenburg of Équipe Paule Ka sustained various injuries in separate training ride crashes and were forced to pull out of the race.