The Vipers played their home games at Raymond James Stadium and were led by head coach Marc Trestman.

In the first week of the season, the Vipers took a loss to the New York Guardians, only scoring a field goal in the 3rd quarter.

Even after the two losses, they put up a fight against the then 2-0 Houston Roughnecks, only losing by a mere 7 points at home.

Tampa Bay entered the game as a 3½ point favorite,[5] but went on to suffer a 20-point blowout loss on the road.

The Vipers suffered 4 turnovers and gave up 3 touchdowns while only getting 1 field goal, despite getting inside the 5-yard line multiple times.