Tampa Bay joined Seattle, Houston, Los Angeles, New York, Dallas, St. Louis and Washington, D.C. as the league's inaugural cities.

On March 5, 2019, Marc Trestman was announced to be the head coach and general manager of the Tampa Bay XFL team for the 2020 season.

On October 15, 2019, The Vipers announced their first player in team history, being assigned former Georgia Bulldogs Quarterback Aaron Murray.

On July 24, 2022, the XFL announced that it would be placing one of its eight teams in the Las Vegas area, and that Rod Woodson would be its head coach.

By the league's own admission, the process of securing a stadium was "long and tedious," as the Vipers had to negotiate around the other teams using Las Vegas's venues (with Allegiant Stadium, Cashman Field, and Bishop Gorman High School being considered at various points), and the XFL was dead-set against having the Vipers play as a traveling team until a venue could be secured.

[11] Both the Vipers players and league president Russ Brandon noted that the field was structurally sound and held up well to the harsh conditions.

[16] The statement did not specify whether the team would be seeking a deal with one of the other stadiums in Las Vegas (as the Houston Roughnecks did in response to their home stadium being slated for renovation[17]) or seeking relocation to another market; if the latter option was chosen, Nashville, Tennessee, Portland, Oregon, and Phoenix, Arizona, were identified as potential candidates to host the team.

[22] On November 30, 2023, Garcia announced via her Instagram page that the leagues had received regulatory approval for the merger and were finalizing plans for a "combined season" to begin March 30, 2024.