This race was one of two Democratic-held U.S. Senate seats up for election in 2020 in a state President Trump won in 2016.

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Tuberville's 20-point margin of victory is largely attributed to the presence of Donald Trump on the ballot, and Jones' votes against Brett Kavanaugh, Amy Coney Barrett, as well as his vote to convict Donald Trump in his first impeachment trial.

Jones was widely considered the most vulnerable senator in 2020, and his victory in 2017 was largely attributed to allegations of child molestation against his opponent.

[137][138][139] With Tuberville lacking such controversies, the state swung hard into the Republican column in 2020,[140] and he flipped 12 counties Jones won in 2017.