The 2021–22 Arkansas–Pine Bluff Golden Lions men's basketball team represented the University of Arkansas at Pine Bluff in the 2021–22 NCAA Division I men's basketball season.

The Golden Lions, led by first-year head coach Solomon Bozeman, played their home games at the H. O. Clemmons Arena in Pine Bluff, Arkansas as members of the Southwestern Athletic Conference.

In a season limited due to the ongoing COVID-19 pandemic, the Golden Lions finished the 2020–21 season 4–21, 3–12 in SWAC play to finish in ninth place.

[1] On April 17, 2021, head coach George Ivory announced his resignation, leaving the program after 13 years at the helm.

[2] On June 11, the school named Oral Roberts assistant Solomon Bozeman as Ivory's replacement.