The 2021–22 Admiral Bet Basketball League of Serbia (Serbian Cyrillic: Кошаркашка лига Србије 2021–22.)

Also, it is the 78th national championship played by Serbian clubs inclusive of the nation's previous incarnations as Yugoslavia and Serbia & Montenegro.

[1] Crvena zvezda mts was the defending champion.

[2] The Playoffs are the second stage of the 2021–22 Serbian League season.

The Super League was canceled due to ABA League schedule conflict and the qualified teams will play in the Playoffs.