The 2021–22 Copa de la Reina was the 37th edition of the Copa de la Reina, Spain's annual field hockey cup competition for women.
It was held from 12 to 14 November 2021, at Real Club de Polo in Barcelona.
[1] Club de Campo won the tournament for a record 18th time, defeating Júnior 4–2 in the final.
[2] Club Egara finished in third place after defeating UD Taburiente 1–0.
[3] The tournament was contested by the top eight ranked teams from the first half of the 2021–22 season of the Liga Iberdrola.