The 2021–22 Kansas Jayhawks women's basketball team represented the University of Kansas in the 2021–22 NCAA Division I women's basketball season.

The Jayhawks were led by seventh-year head coach Brandon Schneider.

They played their home games at Allen Fieldhouse in Lawrence, Kansas as members of the Big 12 Conference.

Kansas made the 2022 NCAA tournament, their first since 2013, losing in the second round to Stanford.

As the ninth seed in the Big 12 Tournament, they lost to TCU in the First Round.