The 2021 Abilene Christian Wildcats football team represented Abilene Christian University in the 2021 NCAA Division I FCS football season as a member of the Western Athletic Conference.

The Challenge included the four fully qualified Division I (FCS) members of the WAC (Abilene Christian, Lamar, Sam Houston, and Stephen F. Austin) and Central Arkansas, Eastern Kentucky, and Jacksonville State of the ASUN Conference.

The winner of the challenge received an auto-bid to the NCAA Division I FCS football playoffs.

[2] The Western Athletic Conference coaches released their preseason poll on July 27, 2021.

[4] Sources: Quarterback Running backs Wide receiver Tight ends Long snappers Offensive lineman Defensive lineman Linebacker Defensive backs Placekickers Punter