Group E of the 2021 Africa Cup of Nations took place from 11 to 20 January 2022.
The group consisted of defending champions Algeria, Equatorial Guinea, the Ivory Coast and Sierra Leone.
[1] The Ivory Coast and Equatorial Guinea advanced to the round of 16.
Notes Man of the Match: Mohamed Kamara (Sierra Leone)[2] Assistant referees: Soulaimane Almadine (Kenya) Lionel Andrianantenaina (Madagascar) Fourth official: Pacifique Ndabihawenimana (Burundi) Video assistant referee: Adil Zourak (Morocco) Assistant video assistant referee: Zakaria Brinsi (Morocco) Man of the Match: Jean Michaël Seri (Ivory Coast)[3] Assistant referees: Lahcen Azgaou (Morocco) Mustapha Akarkad (Morocco) Fourth official: Samir Guezzaz (Morocco) Video assistant referee: Bouchra Karboubi (Morocco) Assistant video assistant referee: Zakaria Brinsi (Morocco) Man of the Match: Nicolas Pépé (Ivory Coast)[4] Assistant referees: Djibril Camara (Senegal) Sidiki Sidibe (Guinea) Fourth official: Issa Sy (Senegal) Video assistant referee: Bakary Gassama (Gambia) Assistant video assistant referee: El Hadj Malick Samba (Senegal) Man of the Match: Iban Salvador (Equatorial Guinea)[5] Assistant referees: Elvis Guy Noupue Nguegoue (Cameroon) Issa Yaya (Chad) Fourth official: Joshua Bondo (Botswana) Video assistant referee: Fernando Guerrero (Mexico) Assistant video assistant referee: Mohammed Abdallah Ibrahim (Sudan) Man of the Match: Franck Kessié (Ivory Coast)[6] Assistant referees: Zakhele Siwela (South Africa) Souru Phatsoane (Lesotho) Fourth official: Pacifique Ndabihawenimana (Burundi) Video assistant referee: Haythem Guirat (Tunisia) Assistant video assistant referee: Dahane Beida (Mauritania) Man of the Match: Iban Salvador (Equatorial Guinea)[7] Assistant referees: Mahmoud Ahmed Abouelregal (Egypt) Ahmed Hossam Taha (Egypt) Fourth official: Mahmoud El Banna (Egypt) Video assistant referee: Mahmoud Mohamed Ashour (Egypt) Assistant video assistant referee: Ahmed El Ghandour (Egypt)