The 2021 Arizona Lottery 100 was a ARCA Menards Series West race held on November 6, 2021.

It was the ninth and final race of the 2021 ARCA Menards Series West season.

Jesse Love clinched the 2021 ARCA Menards Series West championship in a tie-breaker with Jake Drew.

Practice and qualifying were combined into 1 90-minute session, where the fastest lap counted as the driver's qualifying lap.

Ty Gibbs collected the pole with a time of 26.654 and a speed of 135.064 mph (217.364 km/h).