The 2021 General Tire 150 was an ARCA Menards Series race held on March 12, 2021.

Contested over 150 laps on the 1.022-mile (1.645 km) oval, it was the second race of the 2021 ARCA Menards Series season.

Ty Gibbs was fastest in practice with a time of 26.978 seconds and a speed of 133.442 mph (214.754 km/h).

[3] Qualifying was cancelled due to rain.

Ty Gibbs earned the pole for the race, as starting lineup was determined by practice times.