Due to COVID-19 regulations, the tournament was moved to Richmond, Virginia and was set to be played entirely at the Robins Center and Siegel Center, respectively homes of A-10 members Richmond and VCU.

The A-10 later announced that it had swapped the dates of its men's and women's tournaments.

The bulk of the men's tournament was now played at the aforementioned Richmond venues from March 3 through 6.

Any team that did not play above 60 percent of the median number of conference games played by other members would be seeded by their NET ranking within the conference rather than by winning percentage, but all teams ultimately qualified to be seeded by winning percentage.

The top 10 teams received a first-round bye and the top four teams received a double-bye, automatically advancing them to the quarterfinals.