The 2021 BrakeBest Brake Pads 159 presented by O'Reilly was the 2nd stock car race of the 2021 NASCAR Camping World Truck Series season and the 2nd iteration of the event.

The race was extended from 44 to 51 laps due to a NASCAR overtime finish.

[1] To fill out the podium, Sheldon Creed of GMS Racing and John Hunter Nemechek of Kyle Busch Motorsports would finish 2nd and 3rd, respectively.

The race would mark the NASCAR Camping World Truck Series debuts for Lawless Alan[2] and Jett Noland.

[5] Although the Trucks did not have an Auto Club race, their round at Homestead–Miami Speedway was replaced for logistics reasons as Homestead weekend was moved back one week in order to keep the teams in Daytona a second consecutive week.