The 2021 SpeedyCash.com 220 was the 11th stock car race of the 2021 NASCAR Camping World Truck Series season, and the 25th iteration of the event.

The race was held on June 12, 2021 in Fort Worth, Texas at Texas Motor Speedway, a 1.5 miles (2.4 km) permanent quad-oval racetrack.

At race's end, John Hunter Nemechek of Kyle Busch Motorsports would win his 10th race overall in the NASCAR Camping World Truck Series and his 4th of the season.

The track measures 1.5 miles (2.4 km) around and is banked 24 degrees in the turns, and is of the oval design, where the front straightaway juts outward slightly.

As a result, John Hunter Nemechek of Kyle Busch Motorsports would win the pole.