It took place from January 31 to February 6, 2021, at Estadio Teodoro Mariscal in Mazatlán, Mexico.

Spectators were allowed to attend games, though the stadium only operated at 45% of capacity due to COVID-19 restrictions.

Face coverings and socially distanced seating guidelines were enforced.

The 2020–21 Panamanian Professional Baseball League season was canceled due to the ongoing COVID-19 pandemic.

Mike Alvarez was born in Cuba, but raised in the United States.