On 7 June 2021, before dawn, two trains collided near Daharki, in the Ghotki District of the southern province of Sindh in Pakistan, killing at least 65 people and injuring about 150 others.

An investigation report done by Dr Omer M Qureshi/Automotive Design and Crash-worthiness Research determined that the initial derailment had been caused by the failure of a welding joint.

[8][9][6][10] Due to corruption and mismanagement, the railway system sees frequent accidents, and a lack of investment exacerbates issues.

[6][10] Prime Minister Imran Khan had also promised to modernise the railways, but accidents had continued to occur since he took office in 2018, including a train fire in 2019 that killed more than 70 people.

[9][10][11] Habibur Rehman Gilani, chairman of Pakistan Railways, stated that the tracks around the site of the accident were old and needed to be replaced.

[12][15][6][1][2] About a minute later and travelling in the opposite direction, the Sir Syed Express, which had left Rawalpindi bound for Karachi, crashed into the derailed train.

[2] Ghotki deputy commissioner Usman Abdullah stated that 13 or 14 bogies had derailed due to the accident, and 6 to 8 of them had been "completely destroyed".

[25] Federal Minister for Railways Azam Khan Swati stated that a "high-level inquiry" has been ordered to determine how the collision occurred, adding that it was unclear if the accident was a result of sabotage or the track's poor quality.

[6] An initial investigation report stated that the failure of a welding joint on the right side of the northbound tracks caused the derailment of the Millat Express.