The Women's C1 at the 2021 ICF Canoe Slalom World Championships took place on 23 and 26 September 2021 at the Čunovo Water Sports Centre in Bratislava.

2020 European Champion Gabriela Satková of the Czech Republic won bronze, her first individual medal at world championship level.

[2] Andrea Herzog of Germany entered the event as the reigning world champion, having taken the title in 2019 in La Seu d'Urgell.

[3] This was the first World Championships since women's C1 made its Olympic debut at Tokyo, where Jess Fox won gold ahead of Mallory Franklin and Herzog.

Athletes start in the reverse order of their heats position in the semifinal and complete a single run, with the top 10 advancing to the final.

[9] Fellow countrywoman Mallory Franklin set the second fastest time, ahead of Australian Jessica Fox.