The 2021 Il Lombardia was a road cycling one-day race that took place on 9 October 2021 in Italy.

It was the 115th edition of Il Lombardia and the 37th event of the 2021 UCI World Tour.

[1] It was won by Tadej Pogačar in the sprint against Fausto Masnada.

In the chasing group Adam Yates won the sprint for third place.

This Giro di Lombardia race article is a stub.