The Wildcats played their home games at the Bill Snyder Family Football Stadium in Manhattan, Kansas, and competed in the Big 12 Conference.

[4] Kansas State began with a 15-point lead at halftime with performances by quarterback Skylar Thompson and running back Deuce Vaughn.

[8] Kansas State dominated on defense and Stanford's offense continued to make mistakes while not producing a strong running game performance.

Specifically, the paper published "The Kansas State football team opened its season with a statement victory on Saturday at AT&T Stadium.

Before the game, SIU head coach Nick Hill said his team will focus on running: "We're gonna to try to establish [sic] the line of scrimmage and run the ball, but ultimately it's our job to move the ball, whatever you've gotta do.

[9] Kansas State was leading 21–3 in the second quarter when starting quarterback Skylar Thompson left the game with an injured knee.

With backup quarterback Will Howard stepping in, SIU pulled ahead at halftime 23–21 with multiple mistakes for Kansas State.

[14] SIU failed to score in the second half and Kansas State was able to pull ahead to win 31–23.

Jules returning a 41-yard interception for the team's first defensive touchdown since 2018, and safety Qua Brown produced a team-high nine tackles in the game.

[15] In the week prior, Nevada completed their second win of the season by defeating Idaho State by a score of 49–10 and is at the top of the Mountain West Conference with a 2–0 record.

[22] Kansas State spent most of the game on the ground, led by Deuce Vaughn with 127 yards and one touchdown.

It was in the fourth quarter when Kansas State made a clear statement for victory by scoring three touchdowns.

K-State Coach Klieman said, "We challenged the guys early in the week that we needed to take the next step as a football team.

[32] Skylar Thompson returned from injury to start the game at quarterback and developed a 7–3 lead early on, keeping the score tied at 10–10 until just before halftime when Oklahoma managed a field goal to pull ahead 13–10.

OU head coach Lincoln Riley then challenged the replay call for double-touching, claiming that Kansas State kicker Zentner contacted the ball twice while kicking it.

The Iowa State offensive line was given credit for not allowing any sacks and giving quarterback Brock Purdy time to work.

On the ensuing kickoff, Malik Knowles fumbled and Tyrique Matthews recovered the ball at the 23-yard-line which led the Red Raiders to be up 14–0.

Kansas State brought standout great individual performances from Skylar Thompson, Deuce Vaughn, Felix Anudike-Uzomah and a punt by Ty Zentner.

It speaks volumes about where we're at as a program and the type of players we have.” – Skylar Thompson[45] The final score was 25–24, a one-point victory for Kansas State.

Texas Tech responded by firing head coach Matt Wells with his current record of 5 wins and 3 losses.

TCU's previous game was a 29–17 home loss to West Virginia with three turnovers gave up 229 rushing yards.

TCU managed to pull within 7–3 in the second quarter, but Kansas State made it 14–3 on the next series with a 42-yard run by Deuce Vaughn.

[49] On Sunday after the game, TCU fired head coach Gary Patterson and will have Jerry Kill take over on an interim basis.

[57] Kansas State won the game 35-10 and dominated in other statistics along the way: The Wildcats managed 10 yards per play in the first three quarters,[58] went 6–9 on third downs and piled on 499 total yards[54] West Virginia arrived at Kansas State with what was called a "must-win game" but failed to produce the victory.

The Mountaineers will need to beat the Kansas Jayhawks and Texas Longhorns to become bowl eligible.

[61] West Virginia's troubles began on the second play of the game, when Kansas State's Russ Yeast grabbed an interception from a pass that bounced off Winston Wright Jr. Later on, Kansas State's Ty Bowman blocked a punt that was picked up by teammate Marvin Martin who ran it in for a special teams touchdown.

[61] Kansas State coach Klieman recognized that when he said, “This is a big-time win because we haven't had a whole lot of success against them.”[62] In the previous week's game, Baylor defeated the then-ranked No.

Kansas State's regular season record concluded at 7-5 (4–5 in conference) and expect a bowl game invitation on December 5.

[77] Coach Klieman remarked, “I am really proud of our team, especially our seniors, and our staff for their dedication throughout the season and display of our four core values – Discipline, Commitment, Toughness and Be Selfless.