The 2021 Le Samyn was the 53rd edition of the Le Samyn road cycling one day race in Belgium.

It was a 1.1-rated event on the 2021 UCI Europe Tour and the first event in the 2021 Belgian Road Cycling Cup.

[2] The 205.4 kilometres (127.6 mi) long race started in Quaregnon and finished in Dour, with almost four laps of a finishing circuit that featured several cobbled sections and climbs.

All but five teams entered the maximum squad of seven riders; these five teams are Arkéa–Samsic, Cofidis, Delko, Leopard Pro Cycling, and Rally Cycling, each entering six riders.

[4][5][6] UCI WorldTeams UCI ProTeams UCI Continental Teams This cycling race article related to Belgian cycling is a stub.