The tournament was held in Kigali, Rwanda from 7 to 14 September 2021.
The top two teams of the tournament qualified for the 2022 FIVB Volleyball Men's World Championship as the CAVB representatives.
Ranking from the previous edition was shown in brackets except the host and the teams who did not participate, which were denoted by (–).
The host country and the top 8 ranked teams were seed in the Serpentine system.
The 10 remaining teams were drawn in Kigali, Rwanda on 6 September 2021.