The 2021 North Carolina Central Eagles football team represented North Carolina Central University as a member of the Mid-Eastern Athletic Conference (MEAC) during the 2021 NCAA Division I FCS football season.

Led by second-year head coach Trei Oliver, the Eagles compiled an overall record of 6–5 with a mark of 4–1, placing second in the MEAC.

North Carolina Central played home games at O'Kelly–Riddick Stadium in Durham, North Carolina.

[1][2] at Joan C. Edwards Stadium • Huntington, West Virginia

This college football 2020s season article is a stub.