The 2021 North Dakota State Bison baseball team represented North Dakota State University during the 2021 NCAA Division I baseball season.

The Bison play their home games at Newman Outdoor Field adjacent to NDSU's campus.

The team was coached by Tod Brown in his 14th season at NDSU.

[3] They defeated Nevada[4] for the team's first ever NCAA Division I Tournament game win.

Due to the season's cancellation, all Division I college baseball players were granted an extra year of eligibility.