The Monarchs competed in Division I of the National Collegiate Athletic Association (NCAA) and in Conference USA East Division.

They played their home games at Bud Metheny Baseball Complex, on the university's Norfolk campus.

The team was coached by Chris Finwood, who was in his tenth season with the Monarchs.

The Conference USA preseason poll was released on February 11, 2021, with the Monarchs predicted to finish in second place in the East Division.

^ Collegiate Baseball ranked 40 teams in their preseason poll, but only ranked 30 teams weekly during the season.† NCBWA ranks 35 teams in their preseason poll, but only ranks 30 teams weekly during the season.