The Lobos were led by eighth-year[1] head coach John Pearce and played their home hames at Jackson Field in Alpine, Texas.
The Lobos struggled on both sides of the ball throughout the season, with the offense getting shutout twice and the defense allowing 70+ points in two different games.
On November 30, just two weeks after the Lobos' season finale, Pearce announced that he would be resigning as the program's head coach.
[3] On July 24, 2021, the university announced that offensive coordinator Kevin Canty passed away at the age of 37 due to complications from COVID-19.
[4] Valparaiso tight ends coach Barry Derickson was named the Lobos' new offensive coordinator.