The event was held at the Racquet Club of Philadelphia between October 21-28, 2022 and was organised by the United States Court Tennis Association, delayed from its usual March timeslot due to the COVID-19 Pandemic.

[1][2] Due to travel restrictions, the event was only open to players resident in the United States, so was not part of the qualification for the 2023 Real Tennis World Championship.

The men's singles draw was won by incumbent World Champion Camden Riviere for the 9th consecutive time.

[3] Riviere also won the men's doubles draw alongside Tim Chisholm, their 10th US Open title as a pairing.

The edition would be Mike Gooding's final tournament appearance at the US Open before his passing the following year.