In addition to the domestic league, Schalke also participated in this season's edition of the domestic cup, the DFB-Pokal.

This was the 22nd season for Schalke in the Veltins-Arena, located in Gelsenkirchen, North Rhine-Westphalia.

The season covers a period from 1 July 2022 to 30 June 2023.

Schalke were relegated on the final matchday of the season.

Note: Players' appearances and goals only in their Schalke career.