Contested over 150 laps, it was the first exhibition race of the 2022 NASCAR Cup Series season.

On September 14, 2021, NASCAR announced that the Busch Clash would move to the Los Angeles Memorial Coliseum.

[7] On November 9, 2021, the format for the 2022 Clash was announced:[8] Chase Elliott was the fastest in the practice session with a time of 13.455 with an average speed of 66.890 mph (107.649 km/h) .

[9] Kyle Busch scored the pole for the first heat race with a time of 13.745 and a speed of 65.478 mph (105.377 km/h).

Mike Joy, Clint Bowyer, and three-time NASCAR Cup Series champion and Stewart-Haas Racing co-owner Tony Stewart[12] handled the call in the booth for the race, while pit reporters Jamie Little and Regan Smith as well as Larry McReynolds handled interviews.