The Plateau Warriors were the defending champions.
[1] The season began on June 12 and ended July 31, 2022.
[2] Mindelo Monstro won the title after beating Txada Panthers 2–0 in the best-of-three finals.
Two new teams entered the league: Mindelo Monster and Sal Turtles.
They were the first teams from São Vicente and Sal to play in the league.