The 2022 Gran Piemonte was the 106th edition of the Gran Piemonte (known as Giro del Piemonte until 2009) single-day cycling race.

It was held on 6 October 2022, over a distance of 198 km, starting in Omegna and ending in Beinasco.

The race was won by Iván García Cortina of Movistar Team.

[1] 16 of the 18 UCI WorldTeams and seven UCI ProTeams made up the 23 teams that participated in the race.

In total, 156 riders started the race, of which 144 finished.