The 2022 Maryland Cycling Classic was the first edition of the Maryland Cycling Classic.

It was held on 4 September 2022 as part of the 2022 UCI ProSeries calendar.

[1] 4 of the 19 UCI WorldTeams, two UCI ProTeams, nine UCI Continental teams and the American national team made up the 16 teams that participated in the race.

[2] In total, 111 riders started the race.

[3] UCI WorldTeams UCI ProTeams UCI Continental Teams National Teams