The 2022 Grand Prix Cycliste de Québec was a road cycling one-day race that took place on 9 September 2022 in Quebec City, Canada.

It was the 11th edition of the Grand Prix Cycliste de Québec and the 29th event of the 2022 UCI World Tour.

[1] All eighteen UCI WorldTeams, two UCI ProTeams, and the Canadian national team made up the twenty-one teams that participated in the race.

[2] UCI WorldTeams UCI ProTeams National Teams