It convened in Frankfort on January 4, 2022, and adjourned sine die on April 14, 2022.

It was the third regular session of the legislature during the tenure of governor Andy Beshear.

The legislature convened again in August 2022 for an extraordinary session.

Republicans maintained their majorities in both chambers following the 2020 elections for the senate and the house.

Senators in odd-numbered districts were elected in 2020, while senators in even-numbered districts were elected in 2018.