The Bulldogs played their home games at Davis Wade Stadium in Starkville, Mississippi, and compete in the Western Division of the Southeastern Conference (SEC).

In October 2022, 19-year-old freshman offensive lineman Samuel Westmoreland, from Tupelo, Mississippi, committed suicide.

[1] Mississippi State honored Westmoreland with helmet stickers and by painting his initials and number on Scott Field.

[2] On December 11, Leach was hospitalized in critical condition, and Arnett was elevated to interim head coach.

[5] Leach died in the evening of December 12, with Mississippi State announcing the news in a statement the following morning.