The postseason began on December 16, and, aside from any all-star games that are scheduled, ended on January 9, 2023, with the College Football Playoff National Championship at SoFi Stadium in Inglewood, California.

The Georgia Bulldogs successfully defended their national championship when they defeated the TCU Horned Frogs, 65–7.

It was the first time in the College Football Playoff era that a team won back-to-back championships.

The season's Heisman Trophy winner was USC Trojans quarterback Caleb Williams.

James Madison started a transition from Division I FCS in 2022, joining the Sun Belt Conference.

As a full Sun Belt member, it met FBS scheduling requirements in the 2022 season, allowing it to be counted as an FBS opponent for scheduling purposes and to skip the first year of the normal two-year transition process.

Following a brief legal dispute,[38] the parties reached a settlement allowing the schools to leave at the end of June.

The regular season began on Saturday, August 27 with eleven games in Week 0.

On December 4, 2022, the College Football Playoff selection committee announced its final team rankings for the year.

[67] Quarterback Running back All receivers Tight end Lineman: Defensive front Defensive back This is restricted to coaching changes taking place on or after May 1, 2022, and will include any changes announced after a team's last regularly scheduled game but before its bowl game.

This is the final season of the Big Ten's television deal with ESPN, Fox and the Big Ten Network, and Conference USA's television deal with ESPN, Stadium, CBS Sports Network.

Select AAC, MAC and Sun Belt ESPN controlled conference games aired on the network as part of the agreement.