The 2022 New Mexico Lobos football team represented the University of New Mexico as a member of the Mountain West Conference during the 2022 NCAA Division I FBS football season.

They were led by head coach Danny Gonzales, who coached his third season with the team.

The Lobos played their home games at University Stadium in Albuquerque, New Mexico.

New Mexico and the Mountain West Conference announced the 2022 football schedule on February 16, 2022.

This college football 2020s season article is a stub.