On 4 March 2022, the Islamic State – Khorasan Province attacked a Shia mosque at Qissa Khwani Bazaar in Peshawar, Khyber Pakhtunkhwa, Pakistan.

[citation needed] Many major attacks have occurred in Peshawar, the capital and largest city of Khyber Pakhtunkhwa, a province in Pakistan that borders Afghanistan, including a market bombing in 2009 that killed at least 117.

[11] On 4 March 2022 at 12:55 p.m. Pakistan Standard Time (UTC+5),[12] during Friday prayer, a man dressed in black clothing and armed with a pistol[13] arrived near Masjid Asna-e-Ashri in Kucha Risaldar in a motorized rickshaw with two others.

[2] On 5 March 2022, Islamic State – Khorasan Province claimed responsibility for the attack via Amaq News Agency and identified the suicide bomber as Julaybib al-Kabli.

Prime Minister of Pakistan Imran Khan condemned the attack on the mosque and said that he was personally overseeing the situation and coordinating relevant agencies.

[19] Interior Minister Sheikh Rasheed Ahmad condemned the attack and described it as part of a conspiracy to create instability during the Australian national cricket team's first visit to the country in twenty-four years.

[20][21] Due to historical security concerns, including the 2009 attack on the Sri Lanka national cricket team, international events had been held mostly in the United Arab Emirates instead.

[24] Azad Marshall of the Church of Pakistan condemned the attack and urged the government to better secure and protect freedom of religion, which he described as its "fundamental ethical and legal responsibility".

[1][33] Individual condemnations include the Archbishop of Canterbury Justin Welby,[25] Ammar al-Hakim,[34] Muqtada al-Sadr,[35] and Grand Ayatollah Sistani.

[36] The Counter Terrorism Department (CTD) with the assistance of other law enforcement agencies, killed three terrorists in a raid at Regi Lalma area of the Peshawar-Khyber border in Khyber Pakhtunkhwa on 9 March 2022, while trying to enter the city of Peshawar.