The 2022 Pittsburgh Panthers football team represented the University of Pittsburgh as a member of the Coastal Division of the Atlantic Coast Conference (ACC) during the 2022 NCAA Division I FBS football season.

The Panthers were led by eighth-year head coach Pat Narduzzi and played their home games at Acrisure Stadium in Pittsburgh.

This was Pitt's tenth season as a member of the ACC.

The Panthers have signed a total of 12 student-athletes on Early National Signing Day (December 2021) Sources: [1][2][3] [4] at Acrisure Stadium • Pittsburgh, PA at Acrisure Stadium • Pittsburgh, PA at Waldo Stadium • Kalamazoo, MI at Acrisure Stadium • Pittsburgh, PA at Acrisure Stadium • Pittsburgh, PA at Acrisure Stadium • Pittsburgh, PA at Cardinal Stadium • Louisville, KY at Kenan Memorial Stadium • Chapel Hill, NC at Acrisure Stadium • Pittsburgh, PA at Scott Stadium • Charlottesville, VA at Acrisure Stadium • Pittsburgh, PA at Hard Rock Stadium • Miami, FL at Sun Bowl Stadium • El Paso, TX