[1] Jonny Clayton was the reigning champion after defeating José de Sousa 11–5 in the 2021 final,[2] but he lost 10–4 to debutant Joe Cullen in the semi-finals.

[3] On Night 3, Gerwyn Price hit nine-dart finishes in consecutive matches (in his semi-final against Michael van Gerwen and the final against James Wade), making him the second person in Premier League history to hit two nine-darters on the same night, after Phil Taylor, who did both of his in the 2010 Premier League Darts final against Wade.

Instead of the previously used round robin format, the event consisted of an eight-person knockout bracket every night.

[5] Though it was assured that players meet each other only twice in the quarter-finals on regular nights (i.e. weeks 1–7 and 9–15), no other guarantees are made.

The prize money for the 2022 tournament increased to £1 million, including a £10,000 bonus to each night's winner.

[6][7] Usually, the top four players in the PDC Order of Merit following the 2022 PDC World Darts Championship would be joined by six invited players, of which they would have been announced following the World Championship final.

It was revealed that the new format would encompass eight players, each playing against each other in a knockout tournament each night.

The full list of players was announced on 31 January 2022, with the Top 6 players on the PDC Order of Merit joined by the reigning Premier League champion Jonny Clayton, and debutant Joe Cullen, fresh from winning his first televised title at the Masters the previous evening.