The 2022 Settimana Internazionale di Coppi e Bartali was a road cycling stage race that took place between 22 and 26 March 2022 in the Italian region of Emilia-Romagna and in San Marino.

The race was rated as a category 2.1 event on the 2022 UCI Europe Tour calendar, and was the 37th edition of the Settimana Internazionale di Coppi e Bartali.

[1][2] Ten of the 18 UCI WorldTeams, five UCI ProTeams, eight UCI Continental teams, and the Italian national team made up the 24 teams that participated in the race.

[3][4] Of these teams, 16 entered a full squad of seven riders.

Of the 155 riders who started the race,[5] 99 finished.