The Horned Frogs played their home games at Amon G. Carter Stadium in Fort Worth, Texas, and competed in the Big 12 Conference.

After an overtime loss in the 2022 Big 12 Championship Game against Kansas State by a score of 31–28, TCU was selected as the third seed in the four-team College Football Playoff.

In the semifinal round, TCU beat #2 Michigan in the Fiesta Bowl.

TCU lost the National Championship game to the Georgia Bulldogs by a score of 65–7 and finished the season ranked #2 in both the AP and Coaches Polls.

[1][2] 7 Horned Frog players elected to enter the NCAA Transfer Portal after the 2021 season.