The 2022 Tennessee Lottery 250 was the fifteenth stock car race of the 2022 NASCAR Xfinity Series and the 13th iteration of the event.

The race was held on Saturday, June 25, 2022, in Gladeville, Tennessee at Nashville Superspeedway, a 1.333 miles (2.145 km) permanent D-shaped racetrack.

The track was built in 2001 and is currently hosting the Ally 400, a NASCAR Cup Series regular season event, the Tennessee Lottery 250, and the Rackley Roofing 200.

Current permanent seating capacity is approximately 25,000, but will reach up to 38,000 for the NASCAR Cup Series event in 2021.

[5] Sheldon Creed, driving for Richard Childress Racing, was the fastest in the session, with a time of 30.727 seconds, and a speed of 155.824 mph (250.774 km/h).