The 2022 United States Mixed Doubles Curling Championship was held from March 8 to 13, 2022 at Bob Suter's Capitol Ice Arena in Middleton, Wisconsin.

[1] The championship featured twenty-five teams that played in a triple knockout format, which qualified eight teams for the championship round.

From there, four teams advanced to the four team page playoff round.

[2] The winning team, Becca and Matt Hamilton, represented the United States at the 2022 World Mixed Doubles Curling Championship in Geneva, Switzerland.

[3] The teams competing in the 2022 championship were:[4] Source:[5] All draw times listed in Central Time (UTC-06:00).