The PR2 mixed double sculls competition at the 2022 World Rowing Championships took place at the Račice regatta venue.

[1] The schedule was as follows:[1] All times are Central European Summer Time (UTC+2) The two fastest boats in each heat advanced directly to the Final A.

[2] The two fastest boats in heat advanced to the Final A.

[3] The A final determined the rankings for places 1 to 6.

Additional rankings were determined in the other finals.