The 2022 Zamboanga Family's Brand Sardines season was the third season of the franchise in the Maharlika Pilipinas Basketball League (MPBL).
After reaching the division semifinals in their previous campaign, Zamboanga opened their 2022 season with an eight-game winning streak.
The Family's Brand Sardines then finished with a ten-game winning streak to cap off with an 18–3 record and the top seed in the South Division.
After sweeping Muntinlupa and then defeating Bacolod in a three-game series, Zamboanga faced against the Batangas City Embassy Chill for the third consecutive season.
[4] The team played all of their home games this season at the Mayor Vitaliano D. Agan Coliseum in Zamboanga City.